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Schachtrup et al., 2010)

Once-daily oral dosing integrates seamlessly into existing supplement routines without the psychological barriers, technical demands, or lifestyle disruptions associated with injection protocols

portocaval shunt) occurred rapidly

Tzang 2025 (18 RCTs): overweight/obesity regains +5.63 kg while type 2 diabetes regains +2.03 kg but rebounds harder on blood-sugar control (HbA1c +0.65 vs +0.25%)

An M2 to M1 phenotypic shift in microglia is associated with white matter injury after stroke in both young and aged mice [62]

Patients should be advised to contact their GP if neurological symptoms worsen or new symptoms develop despite treatment