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In the highest-dose group, 16% of people stopped taking retatrutide because of side effects, while no one in the placebo group stopped for this reason

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GLP-1s tend to work best when paired with ongoing nutrition, activity and behavioral support

Additionally, during the 68-week treatment period, although weight loss slowed, it did not plateau, suggesting that a longer treatment period may be necessary to achieve the maximum benefits of semaglutide 2.4 mg in this patient population, which this trial did not capture

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