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It means that obesity is a chronic condition that requires ongoing management

( G ) Weight gain of male ( n = 14/17) and female ( n = 15/11) F10 f/f Villin Cre and littermate F10 f/f control mice on a HFD for 14 weeks

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The glucagon arm appears to contribute substantively to body-composition outcomes (favouring fat-mass reduction) without offsetting the glycemic outcomes of the GLP-1/GIP arms (PMID 39515565, PMID 40609566)

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