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15 In acute viral infections such as SARS and MERS, individuals with severe illness exhibited higher viral loads and prolonged viral shedding in respiratory secretions compared to those with mild disease

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The PPP is tightly linked to cysteine metabolism and GSH homeostasis by providing NADPH, which is essential for the regeneration of GSH from its oxidized form, GSSG (Perl 2013) (Fig

Collectively, these processes determine the architecture and functional output of cardiac tissue[135]