Whos tried it or thinking about it
And the best way to maintain lean muscle mass is to eat enough protein and to do strength training exercises
For example, when the growth hormone (GH)/Insulin like growth factor (IGF)-1 axis and insulin resistance were measured after intermittent fasting and caloric restriction over two years in non-diabetic obese subjects, metabolic parameters were positively impacted by caloric restriction, while intermittent fasting (with no caloric restriction) enhanced cellular resistance to disease but without weight loss [56]
Jackevicius CA, Krumholz HM
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Gaining weight on semaglutide is possible, even though the medication is designed to reduce appetite and promote weight loss