Litvinchuk et al., 2024), oligodendrocyte myelination impairment (Blanchard et al., 2022), lowered vascular integrity (Montagne et al., 2021), mitochondrial dysfunction (Schmukler et al., 2020) and pathological interaction with Tau and A, many of which have been covered in numerous reviews (Blumenfeld et al., 2024
Notice that the two strongest cells REDEFINE 1 and SURMOUNT-1 are equally well-designed but structurally uncomparable: different sponsors, sites, durations, and comparator arms
The program also offers alternative weight-loss medication options for patients who are unable or prefer not to take GLP-1 medication and includes genetic testing and treatment for patients meeting criteria for monogenic obesity (early-onset obesity)
Further studies, including final evaluations from regulatory bodies, are warranted to discard a causal link between GLP-1RA and suicidality (shortly before publication of this article, EMA released a news report in line with our findings [39])
Ferroptosis: a regulated cell death nexus linking metabolism
Getting Your Calculations Right Here's where a lot of people get nervous, and rightfully so