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Prespecified subgroup analyses were stratified by duration of GLP1-RA or DPP4i use (at least 6-months, 1-year, and 2-years of use) within their respective groups

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This is likely due to the fact that normal functions of FGF19 include enhanced energy expenditure via actions within anorexigenic (-MSH) neurons in the hypothalamus

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Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes

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