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Sikiri P, Petek M, Rucman R, et al

This finding is consistent with the growing body of evidence linking gut microbiota transformations of dietary polyphenols to systemic metabolic effects [17]

A person who has lost 50 pounds may burn 200-400 fewer calories daily than someone who naturally weighs that amount

You can be born with bad genes, you can eat and drink too much, or you just dont get exercise, but weight is a big part of it, explained Michael Kane, PharmD, a professor at the Albany College of Pharmacy and Health Sciences in New York who specializes in diabetes and osteoporosis and was not involved in this latest research

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The article lists nausea, vomiting, constipation and diarrhea as the symptoms that appear more often as the amount increases, which is why it describes documented tolerability at lower amounts as a prerequisite before a provider considers intensifying therapy