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Curr Med Chem 2012

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Compared with a placebo or non-user comparator, this design minimizes immortal time bias and confounding by balancing disease severity or treatment eligibility in two groups, providing a more reliable real-world estimate of relative effects

Discussion Inflammation caused by degradation products of red blood cells (RBCs) following intracerebral hemorrhage leads to severe secondary brain injury, which is a major reason leading to neuronal apoptosis and worsening prognosis of ICH [24]

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