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Saxenda may fail to suppress appetite due to insufficient dosing (not yet at the 3.0 mg maintenance dose), incorrect injection technique, improper medication storage, dietary factors such as low protein or fibre intake, psychological stress, inadequate sleep, or underlying medical conditions like hypothyroidism or PCOS

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Clinical trials have demonstrated substantial reductions in hemoglobin A1c (up to 2.5% reduction) and body weight (up to 20% reduction) compared to placebo and active comparators