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In mice, a gestational obesity model fed from the preimplantation to lactation with a high-fat diet, induced a higher density of immature neurons in males and a lower density of mature neurons in the dentate gyrus with an increased density of astrocytes and microglia in the hippocampus of both male and female adult offspring (179)

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The sections were blindly screened, examined for histopathological alterations, and scored by an experienced pathologist