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In addition, tumor cells in the bone metastatic niche hijacked VCAM1 + CD163 + CCR3 + macrophages of the erythroblastic islands, which usually supply iron to erythroblasts, disrupting iron homeostasis within the hematopoietic niche, impairing erythropoiesis and contributing to cancer-associated anemia [75]

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According to data from the Centers for Disease Control (CDC), approximately 1 in 31 children 8 years of age (3.2%) were identified as having Autism Spectrum Disorder (ASD)