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797 Even neonatal rat ventricular muscle cells with low sensitivity to GPX4 inhibition underwent ferroptosis in the presence of cysteine deprivation, suggesting that inhibition of GPX4 promotes ferroptosis of cardiomyocytes under metabolic stress, such as cysteine deprivation

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Two decades later Joseph von Mering and Oscar Minkowski, two German physicians based at the University of Strasbourg, showed in a dog that the surgical removal of the pancreas, known as a pancreatomy, immediately caused severe and fatal diabetes

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