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Alcohol consumption was assessed only once, prescription records did not confirm medication adherence, residual confounding remained possible, and the All of Us cohort is not nationally representative

Anjum et al., 2010, 2012a

in this study, vitamin C alone significantly reduced the proliferation, migration and invasion of HCC cells while vitamin C in combination with Lenvatinib showed a synergistic relationship in inhibiting cancer cell proliferation

Deletion of the WT IR allele was induced by treatment with 4-hydroxytamoxifen (4-OHT), resulting in more efficient IR knockout