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2.5 Dry eye disease (DED) One of the main causes of eye care visits is dry eye disease (DED), a complex ailment of the ocular surface and tear film that causes pain, visual disturbances, tear film instability, and possible ocular surface damage [34,35,36]

16 In the premarket drug trial on dabigatran vs warfarin among 18,000 patients with atrial fibrillation, dabigatran was either equally or more effective in reducing stroke and systemic embolism than warfarin, but produced slightly higher values of patients with myocardial infarction

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PLoS ONE 12 , e0170622 (2017)

This process releases vasoactive peptides, including substance P, neurokinin A, and calcitonin gene-related peptide (CGRP)