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The long-acting DAC form delivers a continuous multi-day signal and cannot be timed against a pulse

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Cells were mixed with 2 g of GFP-LC3B (Beyotime Biotechnology) and 100 nM Mito-Tracker Red CMXRos, then treated with the indicated concentrations of PTX to detect mitochondrial and autophagosome co-localization

This process can increase basal metabolism and heat production (thermogenesis), which can result in increased sweating as a means for the body to regulate its temperature