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The results demonstrated that SIRT1 mRNA exhibited a significantly faster decay rate in the absence of SYNCRIP than in control cells, indicating that SYNCRIP plays a critical role in protecting SIRT1 mRNA from rapid degradation (Figure S9C-E)

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Variants in the GLP1R gene (rs6923761) and the GIPR gene (rs1800437) correlate with differing tolerability profiles across clinical populations, meaning some individuals may feel comfortable lying down immediately while others need upright positioning for comfort