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AOD-9604 handles direct fat cell mobilization

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Kiuchi T, Sei H, Seno H, Sano A, Morita Y

It works by exposing the immune system to gradually increasing doses of whole allergen proteins, eventually inducing tolerance

While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

Standardized training requirements could address these gaps (Agarwal et al., 2019)