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Sanyal and colleagues reported the MASLD Phase 2a in Nature Medicine documenting hepatic steatosis reduction (PMID 38858523)

A patient with lower receptor sensitivity might need a higher dose to feel appetite suppression, while someone with higher sensitivity might thrive on a microdose

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Urinary or plasma methylmalonic acid (MMA), a substance produced in the body thats dependent on B12, is also helpful for detecting early stages of B12 deficiency

This program aired on February 28, 2025.

Obesity Epidemic - Global obesity rates have nearly tripled since 1975 and are projected to impact over half the population by 2035