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NICE guidance on obesity management (CG189) supports calorie-reduced diets as a first-line intervention and recommends a deficit of approximately 600 kcal per day below estimated requirements as a practical and sustainable target for most adults

V., Patel, Y., Gaziano, J

S.P.: no competing interests

SOD2, mitochondrial superoxide dismutase

According to Frost & Sullivan data, according to the 2012 American Academy of Sleep Medicine judgment criteria, from 2020 to 2025, the number of people aged 30-69 years old worldwide is expected to increase from 1.07 billion to about 1.16 billion

The postbiotic may support gut health in ways that fiber alone does not, particularly for people with existing dysbiosis where the bacterial populations needed to ferment fiber are depleted