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123 Besides, oxidative stress conditions also increase the innately high IDH1 expression, and IDH1 silencing significantly enhances cell sensitivity to cancer chemotherapy, radiotherapy, and photodynamic therapy by reducing NADPH

Persistent ER stress promotes the extensive release of Ca 2+ into the cytoplasm via the IP3R channel

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Liposomal glutathione capsules, when used judiciously and supported by NAC and liposomal vitamin C, represent a scientifically grounded, practice-friendly strategy to address this overload