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Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): A randomized clinical trial

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When to seek medical advice : Contact your GP or diabetes specialist promptly if you experience: Severe, persistent vomiting or diarrhoea leading to dehydration Severe abdominal pain, particularly if radiating to the back (potential pancreatitis) Signs of hypoglycaemia (if taking insulin or sulphonylureas concurrently) Symptoms of gallbladder problems (pain in the upper right abdomen, fever, yellowing of skin) Any changes in vision (rapid improvement in blood glucose can sometimes worsen diabetic retinopathy) [20] Unexplained persistent nausea beyond the first few weeks If you are planning pregnancy, discuss this with your healthcare provider as GLP-1 RAs are not recommended during pregnancy or breastfeeding

Mroz, P

Functional autoradiography of neuropeptide Y Y1 and Y2 receptor subtypes in rat brain using agonist stimulated [35S]GTPgammaS binding

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