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50 Infected patients often develop worsening of their encephalopathy 51 without fever or elevated white blood cell count

Make sure patients understand exactly what off-label use means, what risks and benefits there are, and what the alternatives look like

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Additionally, the stress of dietary changes can sometimes trigger temporary hair thinning in sensitive individuals

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Although their effects are not immediate, when taken in small doses, they often become apparent after many years or generations of exposure, and remain poorly understood [425]