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These reviews also looked at the risk of depression

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The ratio of reduced to oxidized glutathione serves as a key indicator of the cellular redox potential, with even small changes in the GSH:GSSG ratio influencing protein function by altering cysteine oxidation and disulfide bond formation ( de novo synthesis, GSH degradation and metabolism, the uptake and export of GSH and GSSG and the efficient reduction of GSSG

More research is needed to clarify this paradox (26, 27)

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