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Individuals with reduced activity of the DHFR enzyme, which is responsible for the first step in folic acid metabolism, may be less able to convert folic acid efficiently

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The amino acid plays an important role in the body with methyl group metabolism, which is essential for normal liver and neurological function

doi: 10.1158/0008-5472.CAN-16-1979 183 MustacichDPowisG

These drugs can cause serious side effects and can interact with other medications

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