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Neurological symptoms may take 36 months to fully resolve, and some nerve damage may be permanent if treatment was delayed beyond 12 months

Results from a 2017 study show an association with consuming high-dose B6 and B12 vitamin supplements over 10 years with an increase in lung cancer risk in men, especially smokers (Brasky, 2017)

The upregulation of VEGF by AHK-Cu might imply an enhanced potential for angiogenesis, which could influence nutrient and oxygen supply at the cellular level

Most patients tolerate it very well with minimal discomfort

Some individuals require slower escalation, extending each phase beyond four weeks if side effects remain problematic