2 1 JDMM BMI200320152015BMI25BMI22 303402 GLP-12GLP-1GLP-1 GLP-1111GLP-1 GLP-1 GLP-12 GLP-1 GLP-1 2GLP-1 GLP-1 210GLP-14GLP-1 GLP-1 2393GLP-14 GLP-1GLP-1DPP-4 :LiraglutideDPP-42 3827(5,032)129(2,091)24HbA1cHbA1c 0.9mg:LiraglutideDPP-4(:Vildagliptin:Sitagliptin:Linagliptin:Alogliptin:Teneligliptin:Trelagliptin:Omarigliptin) 2:Liraglutide0.9mgDPP-4 1HbA1c7% GLP-1HbA1c1HbA1c7.0%CCPI,100C/HbA1c7.0%SU1.861.10 GLP-1 GLP-1 GLP-1GLP-1GLP-1 BMI 25kg/m257 150mg/dL2200mg/dL0.3mg/10.3mg/0.9mg/ GLP-1 GLP-12 GLP-1212GLP-1371.59kg GLP-1 GLP-1 GLP-1LEADERSUSTAIN-6 24 24 14GLP-1DPP4GLP-1GLP-1GLP-1 GLP-14 2 SU10 UKPDS24,209 SU2,729met3421,13810 Holman RR et al.N Engl J Med 359(15)1577-1589, 2008 21013159242 50% GLP-130 GLP-1 23HbA1c7%1,168 HbA1c7%6Hb1Ac7% Pantalone KM, et al
This slow titration allows your gastrointestinal system to adjust, reduces nausea and vomiting, and gives your provider time to monitor your progress
Ohyagi Y, Miyoshi K, Nakamura N
The presence or absence of dry mouth doesn't predict your treatment successyour clinician monitors actual weight loss and metabolic improvements to assess whether your semaglutide dose is optimal
While most AMD cases (90%) begin as the less aggressive dry type, around 10% progress to the vision-threatening wet form
The good news is that Retatrutide improves insulin sensitivity over time, meaning response often improves the longer you use it