doi: 10.1056/NEJMoa1612917 18 HernandezAFGreenJBJanmohamedSD'AgostinoRBGrangerCBJonesNPet al
Activates GLP-1 receptors in the hypothalamus, reducing appetite
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However, the long-term effect does not involve the MC4R, which indicates that AgRP likely induces long-term changes to the neural signaling pathways downstream of this receptor
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