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2022;15:1430 Lewis AL, McEntee N, Holland J, Patel A

[DOI] [PubMed] [Google Scholar] 30.Joseph N., Zhang-James Y., Perl A., Faraone S.V

According to Woo-Jin Song and colleagues: "Most, if not all effects of GLP-1 and E4 in beta cells appear to require intracellular activation of the adenosine-3-5-cyclic monophosphate (cAMP)- protein kinase A (PKA) signaling pathway by the G-protein coupled receptor of GLP-1, which is highly expressed on pancreatic beta cells

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30 So far, the studies show a mixed effect on cholesterol, with one study showing a small increase in total cholesterol and another study producing a decrease in HDL cholesterol