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doi: 10.1016/j.intimp.2021.107933 57 SchnellAPKohrtSAristodemouATaylorGPBanghamCRMThoma-KressAK

Both semaglutide and tirzepatide can cause gastrointestinal issues such as: nausea, vomiting, and constipation

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G s (DNG s with 8 mutations) was modified as above to stabilize the interaction with subunits