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Together, these data reveal SDN-1 as a putative communication nexus between the germline and its somatic environment to control germ cell fate decisions

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Chronic GCGR activation should increase plasma glucose levels and insulin levels would then need to rise to promote normoglycaemia during tri-agonist treatment, but this is not the case

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Spermidine, a natural polyamine known to decrease with age in various model organisms and humans (Eisenberg et al., 2009