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GHK-Cus gene modulation capacity was documented in a landmark microarray analysis by Pickart et al., identifying 4,000+ gene targets including VEGF upregulation (angiogenesis), SOD2 upregulation (oxidative defense), and downregulation of pro-inflammatory cytokine genes including TNF- and IL-6

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Track a combination of metrics beyond the scale: waist circumference, how your clothes fit, energy levels, and blood glucose patterns if you have a glucose monitor

This fermentation process produces short-chain fatty acids (SCFAs) like butyrate, which are crucial for maintaining the health of the gut lining and reducing systemic inflammation

Daley and colleagues revealed that hyperglycemia triggers Akt2 activation (phosphorylation) in RPE cells, which in turn increases the expression of EMT markers and fibrosis-related proteins via ERK signaling [6]

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