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It may modulate TCA cycle activity via secondary messengers like cAMP, though further validation is needed (263)

2 Use in Preclinical Research In preclinical research, scientists investigate GLP-1R agonists using animal models, most commonly rodent models such as mice and rats, and sometimes nonhuman primate models

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doi: 10.1007/s10142-017-0579-3

However, the cost may be higher or lower depending on the factors mentioned above

Although linear uptake of choline was observed for FLVCR1 and FLVCR2 (Fig S1C), saturation kinetics could not be obtained, despite adding up to 2 mM ethanolamine, which is 1,000-fold above the physiological concentration in blood of 2 M (Fig S1D) (14, 36)