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A 2022 meta-analysis found NMN increased blood NAD+ by 42% and NR by 28% at 500mg daily dosesboth significantly outperform direct NAD+ supplementation in bioavailability

This is significant for increasing B12 levels in individuals unable to absorb B12 from food or supplements due to their bodys condition

The pathogenesis of depression is rooted in the dysregulation of 5-HT, DA, and NE neurotransmitter systems

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Figure 3 Oligomeric A 40 Induces Inflammation Which Is Modulated by GGC Treating human brain cells with oligomeric A 40 significantly decreased the level of the anti-inflammatory cytokine IL-10 (Figure 4A) and increased the levels of the pro-inflammatory cytokines, TNF-, IL-6 and IL-1 compared to non-treated cells (Figures 4BD)