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Vitamin B12 can be converted to coenzyme B12 in tissues, and as such is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine, a reaction which also requires folate

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A positive result is found in about 85-90% of people with pernicious anaemia, but it's not quite as specific as the IFA test because these antibodies can sometimes show up in other autoimmune conditions

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These conditions can affect how the medication is absorbed and utilized by the body, so it is crucial for patients to disclose their medical history to ensure safe and effective treatment