liposomal glutathione studies outperforms plain glutathione in uptake, cell regeneration and systemic availability: evidence from cellular and human models | British Journal of Nutrition liposomal glutathione vs non-liposomal bioavailability

3.2 Anti-inflammatory response 3.2.1 TLR4/TRIF/NF-B signaling pathway It is reported that the progression of UC is closely associated with the TLR4/NF-B signaling pathway which has emerged as a vital target for therapeutic interventions aimed at preventing of UC development

McCord et al., 2020

Glutathione is a powerful antioxidant that helps protect cells from oxidative stress

Statements Author contributions GM, LB and AT contributed to develop the theory, to the design and implementation of the research and to the writing of the manuscript

Curcumin reverses resistance to gemcitabine through various mechanisms such as inhibiting drug efflux pumps, regulating signaling pathways (such as PI3K/AKT), and inducing specific modes of death (such as ferroptosis) ( Another critical consideration is the substantial pharmacokinetic limitations of curcumin, which are one of the core bottlenecks hindering its clinical translation

More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy