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Why Symptoms Do Not Tell the Full Story A nutrient deficiency can develop gradually and may cause vague symptoms: Fatigue may be associated with iron, vitamin B12, folate, or vitamin D deficiency, but it can also occur with thyroid disease, diabetes, sleep disorders, infection, depression, or many other conditions

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Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset

To further validate the in vitro findings, an STZ-induced T2DM model in rats was established, and RYGB surgery was performed on T2DM rats, or T2DM rats were alternatively treated with GLP-1R agonist EX-4 and examined glucose metabolism- and lipid metabolism-related indicators were examined