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Supplemented free-form BCAAs may cause a sharp rise in circulating BCAA levels, potentially interfering with the transport of aromatic amino acids across the bloodbrain barrier

Erythrocytes from control subjects were incubated with 10 mmol /L [14C]glucose with or without the addition of methylene blue

In summary, the -interaction with Phe357 and the negatively charged environment surrounding Arg358 significantly enhance the effectiveness of DPP-4 inhibitors

PBS, phosphate-buffered saline

As the key enzyme metabolizing APAP into NAPQI, cytochrome P450 enzymes are also considered to be intriguing target for the treatment of APAP-induced liver injury

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