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The trauma-exposed group demonstrated higher prefrontal GABA and lower prefrontal CBF levels than the healthy control group, with elevated limbic CBF levels also observed in the trauma-exposed group (Supplementary Fig

S3 A ), consistent with our prior findings in cell lines (16)

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While stem cells have been used in orthopaedic surgery and regenerative medicine clinics for many years, exosomes have the potential to supersede them as a treatment for aging joints