the study physician attributed the death to pre-existing coronary artery disease unrelated to the drug, but the FDA's Pharmacy Compounding Advisory Committee cited this "unresolved cardiac signal" in December 2024 as a reason to keep the compound off the approved compounding list
The use of MOTs-C as a companion to GLP-1s, to prevent muscle loss, might get around this shortcoming of GLP-1s, but rigorous research is needed to prove [its effectiveness]
Plan dosing schedule
In the United Kingdom, vitamin B12 deficiency is relatively common, with prevalence varying depending on the population studied and the biochemical threshold used for diagnosis
Each mL of sterile aqueous solution contains: Cyanocobalamin (B12)..........3000 mcg With sodium chloride 0.22% w/v, ammonium sulfate 0.1% w/v, citric acid 0.01% w/v, sodium citrate 0.008% w/v, and benzyl alcohol 1.0% v/v (preservative)
Since the benefits of hydroxocobalamin over cyanocobalamin have become more apparent, the former has become the main substance used in B12 injections in Europe