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Key Insights: Helps lower blood pressure and improve blood circulation Effective in managing hypertension and angina (chest pain) Long-acting drug convenient once-daily dosing Plays a role in reducing the risk of heart attack & stroke Points to Remember: Common side effects include ankle swelling (edema), dizziness, and headache Not suitable for immediate relief of angina Overdose may lead to severe hypotension and complications Why this is important
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Cellular Metabolism & Localization Beyond its antioxidant functions, GSH contributes directly to cellular metabolism
at the same time, since the intracerebral hematoma releases hemoglobin (Hb)-based neurotoxin (Wang 2010), the neural damages secondary to perihematomal edema (PHE) that is caused by BBB disruption also occur in the brain parenchyma, becoming an important cause of morbidity and mortality in patients (Jeon et al., 2021)