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Higher oxalate levels are associated with: Kidney stones, urinary nanocrystals Joint pain, skin issues, retinal changes MRI contrast (gadolinium oxalate formation), chronic effects Mitochondrial dysfunction Endothelial (vascular) changes, atherosclerosis Mast cell activation Inflammation and macrophage activation NLRP3 inflammasome activation Breast cancer (certain types) Lets dive into the study details on each of these

doi: 10.1210/jc.2013-4109 149 GonzlezFNairKSDanielsJKBasalESchimkeJM