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The identification of AGK came about through an investigation of the underlying cause of Sengers syndrome

doi:10.1161/01.HYP.0000235682.47673.ab

RAASis with the maximally recommended or maximally tolerated dose of ACEi or ARB are the standard of care for prevention and treatment of CKD in people with diabetes, and they provide benefit over and above the effect of controlling BP [13]

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Serum levels of angiopoietin-related growth factor are increased in metabolic syndrome