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Moreover, mice with neutrophil-specific Gpx4 haploinsufficiency develop lupus phenotype and inhibition of neutrophil ferroptosis significantly mitigates disease development in lupus-prone mice

It has an enormous capacity to combat oxidative stress and neutralize harmful free radicals

Also, the effects of NADPH metabolism on immune cells in the tumor microenvironment are needed to explore for exploiting novel anticancer opportunities

pylori and amino acid metabolism Amino acids are not merely the foundational building blocks of life, but also serve as dynamic regulators in cellular metabolism, influencing a variety of physiological processes beyond their well-known role in protein synthesis [69]

The pCS can also induce macrophage activation and inhibit the antibacterial immune response of LPS-induced macrophages (66)

In a study by Tsantes et al