Naltrexone is better studied with bupropion (FDA-approved as Contrave), whereas semaglutide monotherapy and tirzepatide combinations have stronger trial support for weight loss efficacy
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In a meta-analysis there were no differences in lowering A1c levels but treatment with basal insulin plus GLP-1 RA led to a significant reduction in body weight, whereas basal insulin plus rapid acting insulin treatment was associated with weight gain (difference -2.95 kg
I have lost 30 pounds and my blood sugar levels have improved significantly
Disclosure: Im a paid contributor to NutritionNC.com and was not compensated by Remedy Meds for this review
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