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Where GLP-1 agonists often produce a sensation of fullness and food aversion (sometimes to the point of gastrointestinal discomfort ), amylin-based satiety typically manifests as a more gentle reduction in hunger drive

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International journal of biological sciences

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Supplementation aside, you should always aim to get the majority of your nutrients from food sources, but when it comes to vitamin B12, that's definitely easier said than done, especially for those following plant-based diets free of all animal products

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