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Uncontrolled type 2 diabetes, active gestational diabetes, or a recent hypoglycaemic event are reasons to avoid this compound entirely without direct clinical oversight

If you are deficient in any of these nutrients, direct glutathione supplementation may not be broken down or recycled efficiently

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Controlled human Phase 1 safety and tolerability trials (single- and multiple-ascending-dose) using pharmaceutical-grade material with systematic adverse-event capture the step that would finally distinguish tolerability in rodents from safety in people

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Deviating from this schedule without medical oversight increases the risk of side effects and makes it harder to identify your optimal dose