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More specifically, we first ranked all aptamers according to their test statistic estimate from the linear regression treatment-effect analysis (change in log protein at week 68 versus baseline)

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Moreover, M2-type TAMs, through the secretion of IGF-1 and IGF-2, activate PI3K/AKT/mTOR signaling and enhance the malignant proliferation and stemness characteristics of cancer cells (74)

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