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There's also substantial evidence connecting B12 status to mood regulation, with deficiency associated with increased risk of depression and anxiety

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Using the method developed by Rabarison and colleagues, 494 the Alzheimer's Association assumed the midpoint of each time frame was the average number of hours for each caregiver within that time frame and then calculated the overall average number of hours of weekly care provided by dementia caregivers in each state

Nature 413 (6857), 739743