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Specifically, the addition of cuprizone (bis-cyclohexanone oxalydihydrazone), to the diet process (66) produces a massive demyelination in different areas of the CNS and particularly in the corpus callosum (67-69)

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doi: 10.1016/s0074-7696(01)09014-3

At the application level, 3D printing technology makes it possible to construct personalized implants with bionic structures, while injectable in situ gels have become an ideal choice for filling deep or irregular tissue defects